NOTE: This report is compiled on an ongoing basis by MLSsoccer.com editors based on club game notes, news reports, and original reporting. The league does not have an official player availability report.
Atlanta United
- OUT: Machop Chol (lower body)
- OUT: Jurgen Damm (lower body)
- QUESTIONABLE: Ezequiel Barco (lower body)
- QUESTIONABLE: Mo Adams (sports hernia)
- QUESTIONABLE: Alec Kann (shoulder)
- QUESTIONABLE: Alan Franco (lower body)
Austin FC
- OUT: Aaron Schoenfeld (left knee)
- OUT: Ulises Segura (left knee)
- OUT: Ben Sweat (ACL)
- OUT: Hector Jimenez (MCL)
- OUT: Daniel Pereira (right knee)
- OUT: Danny Hoesen (left hip)
Chicago Fire FC
- OUT: Stanislav Ivanov (left knee)
- OUT: Kenneth Kronholm (right knee)
- QUESTIONABLE: Ignacio Aliseda (left thigh)
- QUESTIONABLE: Elliot Collier (right leg)
- QUESTIONABLE: Gaston Gimenez (right hip)
FC Cincinnati
- OUT: Franko Kovacevic (hamstring)
- OUT: Maikel van der Werff (sports hernia)
Colorado Rapids
- OUT: Kellyn Acosta (international duty)
- QUESTIONABLE: Steven Beitashour (undisclosed injury)
- QUESTIONABLE: Younes Namli (undisclosed injury)
- QUESTIONABLE: Braian Galvan (undisclosed injury)
- QUESTIONABLE: Lalas Abubakar (undisclosed injury)
- OUT: Kevin Molino (left hamstring)
- OUT: Aidan Morris (left knee)
- OUT: Milton Valenzuela (right thigh)
- QUESTIONABLE: Marlon Hairston (left knee)
- QUESTIONABLE: Perry Kitchen (right thigh)
- QUESTIONABLE: Derrick Etienne (right thigh)
- QUESTIONABLE: Waylon Francis (left thigh)
- QUESTIONABLE: Artur (right hip)
FC Dallas
- OUT: Jesus Ferreira (shoulder)
- OUT: Kyle Zobeck (quad strain)
- OUT: Phelipe (left thigh)
- OUT: Nicky Hernandez (thigh)
- OUT: Matt Hedges (hip)
- QUESTIONABLE: Nkosi Tafari (quad strain)
D.C. United
- OUT: Steven Birnbaum (ankle)
- OUT: Erik Sorga (lower body)
- OUT: Chris Odoi-Atsem (lower body)
- OUT: Nigel Robertha (lower body)
- OUT: Edison Flores (hamstring)
Houston Dynamo FC
- OUT: Sam Junqua (undisclosed)
Los Angeles Football Club
- OUT: Kwadwo Opoku (left knee)
- OUT: Erik Duenas (right ankle)
LA Galaxy
- OUT; Sebastian Lletget (international duty)
- QUESTIONABLE: Jalen Neal (undisclosed)
- QUESTIONABLE: Victor Vazquez (undisclosed)
- QUESTIONABLE: Samuel Grandsir (undisclosed)
Inter Miami CF
- OUT: Robbie Robinson (undisclosed)
Minnesota United FC
- OUT: Ike Opara (undisclosed)
- OUT: Emanuel Reynoso (left knee)
- OUT: Ethan Finlay (left knee)
CF Montréal
- OUT: Luis Binks (knee)
- OUT: Ballou Tabla (groin)
- OUT: Kamal Miller (hip)
Nashville SC
- OUT: Brian Anunga (left quad and knee)
New England Revolution
- OUT: Luis Caicedo (lower body)
New York City FC
- OUT: Heber (knee)
- OUT: Gedion Zelalem (hamstring)
New York Red Bulls
- OUT: Jason Pendant (shoulder)
- OUT: Youba Diarra (hamstring)
- OUT: Aaron Long (Achilles)
- OUT: Florian Valot (knee)
- QUESTIONABLE: Andrew Gutman (hip)
Orlando City SC
- OUT: Alexandre Pato (lower body)
- OUT: Uri Rosell (lower body)
- OUT: Ruan (lower body)
- QUESTIONABLE: Joao Moutinho (lower body)
Philadelphia Union
- OUT: Jack de Vries (concussion protocol)
- OUT: Ilsinho (groin surgery)
- OUT:: Greg Ranjitsingh (knee procedure)
Portland Timbers
- OUT: Cristhian Paredes (left thigh strain)
- OUT: Aljaz Ivacic (athletic pubalgia surgery)
- OUT: Jaroslaw Niezgoda (left ACL surgery)
- OUT: Ismaila Jome (left Achilles tendon surgery)
- OUT: Sebastian Blanco (right ACL surgery)
- OUT: Jeff Attinella (right thigh)
- OUT: Diego Chara (right thigh strain)
- OUT: Larrys Mabiala (left thigh strain)
- OUT: Andy Polo (right thigh)
- QUESTIONABLE: Steve Clark (left thigh strain)
Real Salt Lake
- OUT: Everton Luiz (undisclosed)
- OUT: David Ochoa (international duty)
San Jose Earthquakes
- OUT: Jacob Akanyirige (right hip)
- OUT: Jackson Yueill (international duty)
Seattle Sounders FC
- OUT: Jordan Morris (ACL injury)
- OUT: Jordy Delem (right ACL tear)
- OUT: Stefan Frei (left knee sprain)
- OUT: Nicolas Lodeiro (right knee surgery)
- OUT: Josh Atencio (right quad strain)
Sporting Kansas City
- OUT: Kendall McIntosh (adductor)
- OUT: Gadi Kinda (Heath & Safety Protocol)
- OUT: Alan Pulido (international duty)
Toronto FC
- OUT: Ifunanyachi Achara (ACL surgery)
- OUT: Julian Dunn (hip osteochondral injury)
- OUT: Erickson Gallardo (groin)
- OUT: Dom Dwyer (thigh)
- QUESTIONABLE: Alejandro Pozuelo (thigh)
- QUESTIONABLE: Jonathan Osorio (hip)
- QUESTIONABLE: Omar Gonzalez (thigh)
Vancouver Whitecaps FC
- OUT: Ali Adnan (international duty)
- QUESTIONABLE: Andy Rose (adductor strain)
- QUESTIONABLE: Bruno Gaspar (knee irritation)
- QUESTIONABLE: Jake Nerwinski (right knee tibiofibular sprain)
